Surgical Approaches to Gastrointestinal Stromal Tumors

Gastrointestinal Stromal Tumors - Diagnosis and Surgical Treatment.

Gastrointestinal stromal tumors (GIST) are the most common mesenchymal tumors of the gastrointestinal tract, previously classified as leiomyomas, leiomyosarcomas, leiomyoblastomas or schwannomas. They are now recognized as a distinct entity with origin in the mesodermal interstitial cell of Cajal, cells that express the c-KIT protein (tirozine kinase receptor). The definitive diagnosis is estab...

Surgical Treatment of Gastrointestinal Stromal Tumors (GISTs)

Surgical Approaches to Benign Parapharyngeal Space Tumors-5-Year Experience

Introduction: Various surgical approaches to parapharyngeal space (PPS) tumors are introduced to obtain complete removal with the preservation of the surrounding structures in parapharyngealneoplasms. Here, we will discuss the main techniques and their outcome.   Materials and Methods: This retrospective study was conducted on 78 patients undergone either transoral, tran...

Histological and Immunological Evaluation of Gastrointestinal Stromal Tumors

Background: Gastrointestinal stromal tumors (GISTs) constitute the majority of gastrointestinal mesenchymal tumors. They usually express a proto-oncogen protein called CD117 detected by immunohistochemistry. This study investigated the differentiation of GISTs as well as the risk of aggressive behaviors in GISTs from surgically-treated patients in university affiliated hospitals. Methods: The c...

Surgical options for localized and advanced gastrointestinal stromal tumors.

The development of imitinab has led to a revolution in the management of gastrointestinal stromal tumors (GIST), but surgical resection remains the cornerstone of treatment for patients with localized disease. The principles to surgical treatment of GIST include careful handling of tissues to prevent tumor rupture and resection to negative margins without the need for wide excision. Minimally i...